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Version: 17.06d (Release date: 2017-06-26)
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Formoterol Fumarate Oral (Code C85467)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: Formoterol Fumarate Oral

Definition: The orally bioavailable fumarate salt of formoterol, a long-acting, selective beta2-adrenergic receptor agonist with bronchodilating and potential anti-cachexia and anabolic activities. In addition to formoterol's bronchodilating activity, formoterol exhibits anti-cachexia activity through the inhibition of the ATP-ubiquitin-dependent proteolytic system, which may result in a decrease in protein degradation and muscle cell apoptosis. In addition, formoterol may also increase insulin-like growth factor (IGF) signaling, resulting in an increase in protein synthesis. This agent may also inhibit the calcium-dependent calpain system, resulting in the inhibition of muscle wasting.

Label: Formoterol Fumarate Oral

NCI Thesaurus Code: C85467 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: CL412344  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
APD209
Formoterol Fumarate Oral

External Source Codes: 
PDQ Closed Trial Search ID 644381
PDQ Open Trial Search ID 644381 (check for NCI PDQ open clinical trial info)
NCI META CUI CL412344

Other Properties:
     Name Value (qualifiers indented underneath)
code C85467
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C85467

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