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National Cancer Institute
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Version: 17.06d (Release date: 2017-06-26)
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Natural Killer Cells ZRx101 (Code C85466)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: Natural Killer Cells ZRx101

Definition: A population of activated, immortalized, interleukin-2 (IL-2)-dependent, cytotoxic natural killer (NK) cells with potential antitumor activity. Natural killer cells ZRx101 are derived from NK-92 cells, having been modified to target tumor-associated antigens (TAAs) upregulated in certain types of cancer. The NK-92 cell line was originally isolated from a patient with large granular lymphocytic (LGL) leukemia/lymphoma.

Display Name: Natural Killer Cells ZRx101

Label: Natural Killer Cells ZRx101

NCI Thesaurus Code: C85466 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: CL412341  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Natural Killer Cells ZRx101
NK Cells ZRx101

External Source Codes: 
PDQ Closed Trial Search ID 643814
PDQ Open Trial Search ID 643814 (check for NCI PDQ open clinical trial info)

Other Properties:
     Name Value (qualifiers indented underneath)
code C85466
Contributing_Source CTRP
Semantic_Type Cell
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  


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