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Version: 16.10e (Release date: 2016-10-31)
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TARP 29-37-9V Peptide Vaccine (Code C85463)

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Terms & Properties

Preferred Name: TARP 29-37-9V Peptide Vaccine

Definition: A peptide-based cancer vaccine, consisting of amino acid residues 29 through 37 of T cell receptor gamma alternate reading frame protein (TARP) with a leucine-to-valine substitution at position 9, with potential immunostimulatory and antineoplastic activities. Upon administration, TARP 29-37-9V peptide vaccine may induce a cytotoxic T-lymphocyte (CTL) response against TARP-expressing tumor cells, which may result in decreased tumor cell proliferation. The leucine-to-valine substitution at position 9 of this peptide improves its immunogenicity. The nuclear protein TARP is commonly expressed on prostate and breast cancer cells and is highly immunogenic.

Label: TARP 29-37-9V Peptide Vaccine

NCI Thesaurus Code: C85463 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: CL412335  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
TARP 29-37-9V Peptide Vaccine

External Source Codes: 
PDQ Closed Trial Search ID 643628
PDQ Open Trial Search ID 643628 (check for NCI PDQ open clinical trial info)
NCI META CUI CL412335

Other Properties:
Name Value (qualifiers indented underneath)
code C85463
Semantic_Type Amino Acid, Peptide, or Protein
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C85463

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