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Version: 17.06d (Release date: 2017-06-26)
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Talc (Code C854)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: Talc

Definition: Finely-powdered native hydrous magnesium silicate. When administered into the pleural space, talc initiates an inflammatory reaction, resulting in adhesion of the visceral pleura to the parietal pleura and fibrosis, thereby effectively closing the pleural space and preventing further accumulation of fluid. This agent exhibits no intrinsic antineoplastic activity. (NCI04)

NCI-GLOSS Definition: A mineral, usually used in a powdered form. In cancer treatment, sterile talc powder is used to prevent pleural effusions (an abnormal collection of fluid in the space between the lungs and the chest wall). Sterile talc powder is inserted into the space, causing it to close up, so fluid cannot collect there.

Label: Talc

NCI Thesaurus Code: C854 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0039267  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Sclerosol Intrapleural Aerosol
sterile talc powder
Sterile Talc Powder

External Source Codes: 
CAS Registry Number 14807-96-6 (see NLM ChemIDplus info)
PDQ Closed Trial Search ID 42168
PDQ Open Trial Search ID 42168 (check for NCI PDQ open clinical trial info)
UMLS CUI C0039267

Other Properties:
     Name Value (qualifiers indented underneath)
Accepted_Therapeutic_Use_For Malignant pleural effusion; Pneumothorax
code C854
Contributing_Source FDA
Legacy_Concept_Name Talc
Semantic_Type Biomedical or Dental Material
Semantic_Type Inorganic Chemical
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  


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