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Version: 17.06d (Release date: 2017-06-26)
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MAGE-A1/MAGE-A3/NY-ESO-1 Peptides Vaccine (Code C84854)

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Terms & Properties

Preferred Name: MAGE-A1/MAGE-A3/NY-ESO-1 Peptides Vaccine

Definition: A cancer vaccine comprised of synthetic peptides derived from human melanoma antigen A1 (MAGE-A1), human melanoma antigen A3 (MAGE-A3) and cancer-testis antigen NY-ESO-1 with potential immunostimulating and antineoplastic activities. Upon administration, MAGE-A1/MAGE-A3/NY-ESO-1 peptides vaccine may stimulate the immune system to mount a cytotoxic T-cell (CTL) response against tumor cells expressing MAGE-A1, MAGE-A3 and NY-ESO-1, resulting in tumor cell lysis. The MAGE-A1, MAGE-A3, and NY-ESO-1 tumor-associated antigens (TAAS) are overexpressed by a variety of cancer cell types.

Label: MAGE-A1/MAGE-A3/NY-ESO-1 Peptides Vaccine

NCI Thesaurus Code: C84854 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: CL412412  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
MAGE-A1/MAGE-A3/NY-ESO-1 Peptides Vaccine

External Source Codes: 
PDQ Closed Trial Search ID 651378
PDQ Open Trial Search ID 651378 (check for NCI PDQ open clinical trial info)
NCI META CUI CL412412

Other Properties:
     Name Value (qualifiers indented underneath)
code C84854
Semantic_Type Amino Acid, Peptide, or Protein
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C84854

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