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Version: 16.11d (Release date: 2016-11-28)
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Human Trefoil Factor 1-Secreting Lactococcus lactis AG013 (Code C84842)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: Human Trefoil Factor 1-Secreting Lactococcus lactis AG013

Definition: An oral rinse solution containing a strain of the bacteria Lactococcus lactis (L. lactis) genetically modified to express human Trefoil Factor 1 (hTFF1) with potential cytoprotective activity. With oral rinsing, human trefoil factor 1-secreting Lactococcus lactis AG013 may secrete and deliver hTFF1 to oral mucosal tissue, protecting or promoting the healing of damaged oral mucosa. hTFF1, a peptide belonging to the Trefoil factors family (TFF), is normally secreted by mucous epithelia and is involved in protecting mucosal tissue and maintaining mucosal surface integrity.

Display Name: Human Trefoil Factor 1-Secreting Lactococcus lactis AG013

Label: Human Trefoil Factor 1-Secreting Lactococcus lactis AG013

NCI Thesaurus Code: C84842 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: CL412393  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
AG013
hTFF1-Secreting Lactococcus lactis AG013
Human Trefoil Factor 1-Secreting Lactococcus lactis AG013

External Source Codes: 
PDQ Closed Trial Search ID 650159
PDQ Open Trial Search ID 650159 (check for NCI PDQ open clinical trial info)
NCI META CUI CL412393

Other Properties:
Name Value (qualifiers indented underneath)
code C84842
Contributing_Source CTRP
Semantic_Type Bacterium
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C84842

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