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Version: 17.06d (Release date: 2017-06-26)
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Cannabinol (Code C84510)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: Cannabinol

Definition: A cannabinoid isolated from the plant Cannabis that is a metabolite of tetrahydrocannabinol (THC), with potential immunosuppressive and anti-inflammatory activities. Cannabinol preferentially binds to the cannabinoid G-protein coupled receptor CB2, which is mainly expressed on a variety of immune cells, such as T-cells, B-cells, macrophages and dendritic cells. Stimulation of CB2 receptors by cannabinol may both trigger apoptosis in these cells and inhibit the production of a variety of cytokines. Cannabinol exerts minimal affinity for CB1 and has a weak effect on the central nervous system.

Label: Cannabinol

NCI Thesaurus Code: C84510 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0006865  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
3-Amyl-1-hydroxy-6,6,9-trimethyl-6H-dibenzo(b,d)pyran
6,6,9-Trimethyl-3-pentyl-6H-dibenzo(b,d)pyran-1-ol
Cannabinol
CANNABINOL
CBN

External Source Codes: 
CAS Registry Number 521-35-7 (see NLM ChemIDplus info)
FDA UNII Code 7UYP6MC9GH
NSC Code 134455 (see NCI DTP info)
PDQ Closed Trial Search ID 750101
PDQ Open Trial Search ID 750101 (check for NCI PDQ open clinical trial info)
UMLS CUI C0006865

Other Properties:
     Name Value (qualifiers indented underneath)
Chemical_Formula C21H26O2
code C84510
Contributing_Source FDA
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C84510

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