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Version: 17.12d (Release date: 2017-12-26)
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Sodium Salicylate (Code C834)

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Terms & Properties

Preferred Name: Sodium Salicylate

Definition: The sodium salt of salicylic acid. As a nonsteroidal anti-inflammatory drug (NSAID), sodium salicylate irreversibly acetylates cyclooxygenases I and II, thereby inhibiting prostaglandin synthesis and associated inflammation and pain. This agent may also activate mitogen-activated protein kinase (p38MAPK), thereby inducing apoptosis in cancer cells. (NCI04)

NCI-GLOSS Definition: A drug that is a type of nonsteroidal anti-inflammatory drug. Sodium salicylate may be tolerated by people who are sensitive to aspirin.

Label: Sodium Salicylate

NCI Thesaurus Code: C834 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0037549  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Benzoic acid, 2-hydroxy-, monosodium salt
Salicylate, sodium
Sodium salicylate
Sodium Salicylate
sodium salicylate

External Source Codes: 
CAS Registry Number 54-21-7 (see NLM ChemIDplus info)
NSC Code 202167 (see NCI DTP info)
PDQ Closed Trial Search ID 43094
PDQ Open Trial Search ID 43094 (check for NCI PDQ open clinical trial info)
UMLS CUI C0037549

Other Properties:
     Name Value (qualifiers indented underneath)
Accepted_Therapeutic_Use_For Fever; Inflammatory conditions; Pain
Chemical_Formula C7H5O3.Na
code C834
Contributing_Source FDA
Legacy_Concept_Name Sodium_Salicylate
Semantic_Type Organic Chemical
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  


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