skip navigation links
National Cancer Institute
EVS Logo NCI Term Browser Enterprise Vocabulary Services
Terminologies Value Sets Mappings
Version: 17.02d (Release date: 2016-02-27)
SearchBox Top
SearchBox Bottom
HLA-A2-Restricted Synthetic Glioma Antigen Peptides Vaccine (Code C82661)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: HLA-A2-Restricted Synthetic Glioma Antigen Peptides Vaccine

Definition: A synthetic peptide cancer vaccine consisting of HLA-A2-restricted peptides derived from glioma-associated antigens (GAA) with potential immunostimulating and antineoplastic activities. Upon administration, HLA-A2-restricted synthetic glioma antigen peptides vaccine may stimulate the host immune system to mount a cytotoxic T lymphocyte (CTL) response against tumor cells expressing the corresponding GAAs, resulting in glioma tumor cell lysis. HLA-A2 is an MHC class I molecule that presents antigenic peptides to CD8+ T cells; epitope design restricted to epitopes that bind most efficiently to HLA-A2 may improve antigenic peptide immunogenicity.

Display Name: HLA-A2-Restricted Synthetic Glioma Antigen Peptides Vaccine

Label: HLA-A2-Restricted Synthetic Glioma Antigen Peptides Vaccine

NCI Thesaurus Code: C82661 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: CL411371  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
HLA-A2-Restricted Synthetic Glioma Antigen Peptides Vaccine

External Source Codes: 
PDQ Closed Trial Search ID 636663
PDQ Open Trial Search ID 636663 (check for NCI PDQ open clinical trial info)
NCI META CUI CL411371

Other Properties:
Name Value (qualifiers indented underneath)
code C82661
Contributing_Source CTRP
Legacy_Concept_Name HLA-A2-Restricted_Synthetic_Glioma_Antigen_Peptides_Vaccine
Semantic_Type Amino Acid, Peptide, or Protein
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C82661

Mainbox Bottom