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National Cancer Institute
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Version: 17.06d (Release date: 2017-06-26)
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Selenium (Code C825)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: Selenium

Definition: A nonmetallic chemical element found in trace amounts in human body. Selenium primarily occurs in vivo as selenocompounds, mostly selenoproteins such as glutathione peroxidase and thioredoxin reductase (enzymes responsible for detoxification). Alone or in combination with Vitamin E, selenocompounds act as antioxidants. These agents scavenge free radicals; prevent blood clots by inhibiting platelet aggregation; strengthen the immune system; and have been shown, in some instances, to inhibit chromosomal damage and mutations. Exhibiting chemopreventive activity, selenocompounds also inhibit the induction of protein kinase C.

NCI-GLOSS Definition: A mineral that is needed by the body to stay healthy. It is being studied in the prevention and treatment of some types of cancer. Selenium is a type of antioxidant.

Display Name: Selenium

Label: Selenium

NCI Thesaurus Code: C825 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0036581  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)

External Source Codes: 
CAS Registry Number 7782-49-2 (see NLM ChemIDplus info)
FDA UNII Code H6241UJ22B
ChEBI ID CHEBI:36904 (see ChEBI info)
ChEBI ID CHEBI:27568 (see ChEBI info)
PDQ Closed Trial Search ID 38725
PDQ Open Trial Search ID 38725 (check for NCI PDQ open clinical trial info)
UMLS CUI C0036581

Other Properties:
     Name Value (qualifiers indented underneath)
Accepted_Therapeutic_Use_For Dandruff; Psoriasis; Seborrheic dermatitis; Tinea capitis; Tinea versicolor
Chemical_Formula Se
code C825
Contributing_Source CTRP
Contributing_Source FDA
Legacy_Concept_Name Selenium
Semantic_Type Element, Ion, or Isotope
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  


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