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Version: 17.06d (Release date: 2017-06-26)
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HuaChanSu (Code C82415)

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Terms & Properties

Preferred Name: HuaChanSu

Definition: A traditional Chinese medicine (TCM) containing a water soluble Bufo toad skin extract that includes the cardiac glycosides bufalin, cinobufagin and resibufogenin with potential antineoplastic and antiangiogenic activities. Although the exact mechanism of action of this TCM has yet to be fully elucidated, huachansu, which may be administered in an injectable form, may induce cell cycle arrest and apoptosis by suppressing the expression of anti-apoptotic proteins, such as Bcl-2, while inducing the expression of pro-apoptotic proteins, such as BAX.

Display Name: HuaChanSu

Label: HuaChanSu

NCI Thesaurus Code: C82415 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C2745673  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)

External Source Codes: 
PDQ Closed Trial Search ID 637352
PDQ Open Trial Search ID 637352 (check for NCI PDQ open clinical trial info)
UMLS CUI C2745673

Other Properties:
     Name Value (qualifiers indented underneath)
code C82415
Contributing_Source CTRP
Legacy_Concept_Name HuaChanSu
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  


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