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Version: 17.06d (Release date: 2017-06-26)
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Bone Metastasis Targeting Peptide-11 (Code C82370)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: Bone Metastasis Targeting Peptide-11

Definition: A peptide that mimics naturally occurring interleukin-11 (IL-11) with interleukin receptor binding activity. Upon administration, bone metastasis targeting peptide-11 (BMTP-11) binds to interleukin-11 receptor alpha (IL-11Ra) BMTP-11. This agent might be used to deliver therapeutic agents specifically to IL-11Ra-expressing tumor cells while sparing normal cells. IL-11Ra is a cell surface receptor that may be overexpressed by osteosarcoma cells and by prostate cancer cells in prostate cancer bone metastases.

Display Name: Bone Metastasis Targeting Peptide-11

Label: Bone Metastasis Targeting Peptide-11

NCI Thesaurus Code: C82370 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C2830059  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
BMTP-11
Bone Metastasis Targeting Peptide-11

External Source Codes: 
PDQ Closed Trial Search ID 641166
PDQ Open Trial Search ID 641166 (check for NCI PDQ open clinical trial info)
UMLS CUI C2830059

Other Properties:
     Name Value (qualifiers indented underneath)
code C82370
Contributing_Source CTRP
Legacy_Concept_Name Bone_Metastasis_Targeting_Peptide-11
Semantic_Type Amino Acid, Peptide, or Protein
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C82370

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