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Version: 17.06d (Release date: 2017-06-26)
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Recombinant Human Albumin-Human Granulocyte Colony-Stimulating Factor (Code C81936)

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Terms & Properties

Preferred Name: Recombinant Human Albumin-Human Granulocyte Colony-Stimulating Factor

Definition: A long-acting recombinant fusion protein incorporating human serum albumin (HSA)-derived and human granulocyte colony stimulating factor (G-CSF)-derived moieties with potential granulopoietic activity. G-CSF, a naturally occurring cytokine, stimulates the production of granulocytes and stem cells in the bone marrow and their release into the blood; it also stimulates the differentiation, function, and survival of neutrophil precursors and mature neutrophils. Albumin fusion may promote an increased serum half-life and bioavailability of the G-CSF moiety of this fusion protein.

Label: Recombinant Human Albumin-Human Granulocyte Colony-Stimulating Factor

NCI Thesaurus Code: C81936 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: CL407460  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
GW003
Neugranin
Recombinant Human Albumin-Human Granulocyte Colony-Stimulating Factor

External Source Codes: 
PDQ Closed Trial Search ID 637546
PDQ Open Trial Search ID 637546 (check for NCI PDQ open clinical trial info)
NCI META CUI CL407460

Other Properties:
     Name Value (qualifiers indented underneath)
code C81936
Legacy_Concept_Name Recombinant_Human_Albumin-Human_GCSF
Semantic_Type Amino Acid, Peptide, or Protein
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C81936

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