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Version: 17.06d (Release date: 2017-06-26)
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Almurtide (Code C81667)

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Terms & Properties

Preferred Name: Almurtide

Definition: A synthetic muramyl dipeptide (MDP) analogue with potential immunostimulating and antineoplastic activity. As a derivative of the mycobacterial cell wall component MDP, almurtide activates both monocytes and macrophages. This results in the secretion of cytokines and induces the recruitment and activation of other immune cells, which may result in indirect tumoricidal or cytostatic effects.

Label: Almurtide

NCI Thesaurus Code: C81667 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0130664  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
2-Acetamido-3-O-((((1S)-1-(((1R)-1-carbamoyl-3- carboxypropyl)carbamoyl)ethyl)carbamoyl)methyl)-2-deoxy-D- glucopyranose
Almurtide
ALMURTIDE
Cgp-11637
N-Acetyl-nor-muramyl-L-alanyl-D-isoglutamine
nor-MDP
norMDP

External Source Codes: 
CAS Registry Number 61136-12-7 (see NLM ChemIDplus info)
FDA UNII Code 1DCO35D4OR
PDQ Closed Trial Search ID 702874
PDQ Open Trial Search ID 702874 (check for NCI PDQ open clinical trial info)
UMLS CUI C0130664

Other Properties:
     Name Value (qualifiers indented underneath)
Chemical_Formula C18H30N4O11
code C81667
Contributing_Source FDA
Legacy_Concept_Name Almurtide
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C81667

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