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National Cancer Institute
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Version: 17.06d (Release date: 2017-06-26)
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Telaprevir (Code C81603)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: Telaprevir

Definition: An orally available peptidomimetic small molecule with activity against hepatitis C virus (HCV). Telaprivir is a selective protease inhibitor that targets the viral HCV NS3-4A serine protease and disrupts processing of viral proteins and formation of a viral replication complex.

Display Name: Telaprevir

Label: Telaprevir

NCI Thesaurus Code: C81603 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C1876229  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Incivek
LY-570310
MP-424
Telaprevir
TELAPREVIR
VRT-111950
VX-950

External Source Codes: 
CAS Registry Number 402957-28-2 (see NLM ChemIDplus info)
FDA UNII Code 655M5O3W0U
PDQ Closed Trial Search ID 748913
PDQ Open Trial Search ID 748913 (check for NCI PDQ open clinical trial info)
UMLS CUI C1876229

Other Properties:
     Name Value (qualifiers indented underneath)
Accepted_Therapeutic_Use_For Chronic Hepatitis C
Chemical_Formula C36H53N7O6
code C81603
Contributing_Source CTRP
Contributing_Source FDA
Legacy_Concept_Name Telaprevir
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C81603

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