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Version: 17.06d (Release date: 2017-06-26)
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Riboflavin (Code C808)

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Terms & Properties

Preferred Name: Riboflavin

Definition: An essential human nutrient that is a heat-stable and water-soluble flavin belonging to the vitamin B family. Riboflavin is a precursor of the coenzymes flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD). These coenzymes are of vital importance in normal tissue respiration, pyridoxine activation, tryptophan to niacin conversion, fat, carbohydrate, and protein metabolism, and glutathione reductase mediated detoxification. Riboflavin may also be involved in maintaining erythrocyte integrity. This vitamin is essential for healthy skin, nails, and hair.

NCI-GLOSS Definition: A nutrient in the vitamin B complex that the body needs in small amounts to function and stay healthy. Riboflavin helps make red blood cells, helps some enzymes work properly, and keeps skin, nails, and hair healthy. It is found in milk, eggs, malted barley, organ meats, yeast, and leafy vegetables. Riboflavin is water-soluble (can dissolve in water) and must be taken in every day. Not enough riboflavin can cause anemia (a low number of red blood cells), mouth sores, and skin problems. Amounts of riboflavin may be higher in the blood of patients with some types of cancer.

CRCH Definition: Water-soluble vitamin that is a coenzyme in numerous oxidation-reduction reactions. (DRI)

Label: Riboflavin

NCI Thesaurus Code: C808 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0035527  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
6,7-Dimethyl-9-D-ribitylisoalloxazine
Lactoflavin
Riboflavin
RIBOFLAVIN
riboflavin
Riboflavine
Vitamin B2
vitamin B2

External Source Codes: 
CAS Registry Number 83-88-5 (see NLM ChemIDplus info)
FDA UNII Code TLM2976OFR
ChEBI ID CHEBI:17015 (see ChEBI info)
NSC Code 33298 (see NCI DTP info)
PDQ Closed Trial Search ID 38330
PDQ Open Trial Search ID 38330 (check for NCI PDQ open clinical trial info)
UMLS CUI C0035527

Other Properties:
     Name Value (qualifiers indented underneath)
Chemical_Formula C17H20N4O6
code C808
Contributing_Source CRCH
Contributing_Source FDA
INFOODS RIBF
Legacy_Concept_Name Riboflavin
Micronutrient Y
Nutrient Y
Semantic_Type Organic Chemical
Semantic_Type Vitamin
Unit mg
US_Recommended_Intake Y
USDA_ID 405

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C808

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