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Version: 17.06d (Release date: 2017-06-26)
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Granisetron Transdermal Patch (Code C80377)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: Granisetron Transdermal Patch

Definition: A transdermal system containing granisetron, a selective serotonin (5-HT) receptor antagonist, with antiemetic activity. Upon application of the transdermal patch to the skin and subsequent release into the bloodstream, granisetron selectively binds to and blocks the 5-HT subtype 3 (5-HT3) receptors located in the vagus nerve terminal and in the vomiting center in the central nervous system (CNS). By preventing stimulation of 5-HT3 receptors, this agent is able to suppress chemotherapy-induced nausea and vomiting.

Display Name: Granisetron Transdermal Patch

Label: Granisetron Transdermal Patch

NCI Thesaurus Code: C80377 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C2370075  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
1-Methyl-N-(9-methyl-endo-9-azabicyclo(3.3.1)non-3-yl)-1H-indazole-3-carboxamide
Granisetron Transdermal Patch
Granisetron Transdermal System
Sancuso

External Source Codes: 
CAS Registry Number 109889-09-0 (see NLM ChemIDplus info)
PDQ Closed Trial Search ID 642824
PDQ Open Trial Search ID 642824 (check for NCI PDQ open clinical trial info)
UMLS CUI C2370075

Other Properties:
     Name Value (qualifiers indented underneath)
code C80377
Contributing_Source CTRP
Legacy_Concept_Name Granisetron_Transdermal_Patch
Semantic_Type Organic Chemical
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C80377

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