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Version: 17.06d (Release date: 2017-06-26)
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Gadoterate Meglumine (Code C80124)

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Terms & Properties

Preferred Name: Gadoterate Meglumine

Definition: A gadolinium chelate paramagnetic contrast agent. When placed in a magnetic field, gadoterate meglumine produces a large magnetic moment and so a large local magnetic field, which can enhance the relaxation rate of nearby protons; as a result, the signal intensity of tissue images observed with magnetic resonance imaging (MRI) may be enhanced. Because this agent is preferentially taken up by normal functioning hepatocytes, normal hepatic tissue is enhanced with MRI while tumor tissue is unenhanced. In addition, because gadobenate dimeglumine is excreted in the bile, it may be used to visualize the biliary system using MRI.

Display Name: Gadoterate Meglumine

Label: Gadoterate Meglumine

NCI Thesaurus Code: C80124 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0060929  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
DOTAREM
Gadoterate Meglumine
GADOTERATE MEGLUMINE
Gd-DOTA

External Source Codes: 
CAS Registry Number 92943-93-6 (see NLM ChemIDplus info)
FDA UNII Code L0ND3981AG
PDQ Closed Trial Search ID 618206
PDQ Open Trial Search ID 618206 (check for NCI PDQ open clinical trial info)
UMLS CUI C0060929

Other Properties:
     Name Value (qualifiers indented underneath)
Chemical_Formula C16H24N4O8.C7H17NO5."H".Gd
code C80124
Contributing_Source CTRP
Contributing_Source FDA
Legacy_Concept_Name Gadoterate_Meglumine
Semantic_Type Indicator, Reagent, or Diagnostic Aid
Semantic_Type Organic Chemical

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C80124

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