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Version: 16.11d (Release date: 2016-11-28)
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hTERT Vaccine V934/V935 (Code C80055)

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Terms & Properties

Preferred Name: hTERT Vaccine V934/V935

Definition: A cancer vaccine directed against human telomerase reverse transcriptase (hTERT), the catalytic subunit of human telomerase, with potential immunostimulating and antineoplastic activities. Upon administration, hTERT vaccine V934/V935 may elicit a cytotoxic T cell (CTL) response against telomerase-expressing tumor cells, which may result in tumor cell death. Telomerase is involved in the restoration and maintenance of telomere length and so the functional lifespan of cells. Abnormally reactivated in tumorigenesis, telomerase is expressed in the majority of human cancer cells but is not expressed or is expressed at very low levels in normal cells.

Display Name: hTERT Vaccine V934/V935

Label: hTERT Vaccine V934/V935

NCI Thesaurus Code: C80055 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: CL388391  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
hTERT Vaccine V934/V935
V934/V935

External Source Codes: 
PDQ Closed Trial Search ID 615723
PDQ Open Trial Search ID 615723 (check for NCI PDQ open clinical trial info)
NCI META CUI CL388391

Other Properties:
Name Value (qualifiers indented underneath)
code C80055
Contributing_Source CTRP
Legacy_Concept_Name hTERT_Vaccine_V934_V935
Semantic_Type Immunologic Factor
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C80055

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