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Version: 16.11d (Release date: 2016-11-28)
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6,8-Bis(benzylthio)octanoic Acid (Code C80039)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: 6,8-Bis(benzylthio)octanoic Acid

Definition: A racemic mixture of the enantiomers of a synthetic alpha-lipoic lipoic acid analogue with potential chemopreventive and antineoplastic activities. Although the exact mechanism of action is unknown, 6,8-Bis(benzylthio)octanoic acid has been shown to inhibit metabolic and regulatory processes required for cell growth in solid tumors. Both enantiomers in the racemic mixture exhibit antineoplastic activity.

Display Name: 6,8-Bis(benzylthio)octanoic Acid

Label: 6,8-Bis(benzylthio)octanoic Acid

NCI Thesaurus Code: C80039 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C2703200  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
6,8-Bis(benzylthio)octanoic Acid
6,8-BIS(BENZYLTHIO)OCTANOIC ACID
Alpha-Lipoic Acid Analogue CPI-613
CPI-613
CPI 613

External Source Codes: 
CAS Registry Number 95809-78-2 (see NLM ChemIDplus info)
FDA UNII Code E76113IR49
PDQ Closed Trial Search ID 614265
PDQ Open Trial Search ID 614265 (check for NCI PDQ open clinical trial info)
UMLS CUI C2703200

Other Properties:
Name Value (qualifiers indented underneath)
Chemical_Formula C22H28O2S2
code C80039
Contributing_Source CTRP
Contributing_Source FDA
Legacy_Concept_Name Alpha-Lipoic_Acid_Analogue_CPI-613
Semantic_Type Organic Chemical
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C80039

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