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Version: 17.06d (Release date: 2017-06-26)
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Taltirelin Hydrate (Code C79830)

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Terms & Properties

Preferred Name: Taltirelin Hydrate

Definition: The hydrate of tatirelin, a thyrotropin releasing hormone (TRH) analogue with potential neuroprotective, analgesic and central nervous system-stimulating (CNS)/analeptic activities. Taltirelin mimics the physiological actions of TRH on the CNS while exerting a minimal effect on the release of thyrotrophin (TSH) from the anterior lobe of the pituitary. Like TRH, the mechanism of action of this agent in the CNS has not been fully elucidated mechanism, but may involve various cerebral monoamine pathways. Compared to TRH, taltirelin has a much longer half-life and duration of effects.

Label: Taltirelin Hydrate

NCI Thesaurus Code: C79830 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0961704  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Taltirelin Hydrate

External Source Codes: 
PDQ Closed Trial Search ID 629060
PDQ Open Trial Search ID 629060 (check for NCI PDQ open clinical trial info)
UMLS CUI C0961704

Other Properties:
     Name Value (qualifiers indented underneath)
code C79830
Legacy_Concept_Name Taltirelin_Hydrate
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  


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