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Version: 17.06d (Release date: 2017-06-26)
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Iofolastat I123 (Code C78827)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: Iofolastat I123

Definition: An iodine 123-radiolabeled small molecule that exhibits high affinity for prostate-specific membrane antigen (PSMA) with potential use in molecular imaging. Iofolastat I123, a radiolabeled glutamate-urea-lysine analogue, selectively binds PSMA, which allows imaging of PSMA-expressing prostate cancer cells with gamma scintigraph. PSMA is a transmembrane glycoprotein highly expressed by malignant prostate epithelial cells and vascular endothelial cells of various solid tumors.

Display Name: Iofolastat I123

Label: Iofolastat I123

NCI Thesaurus Code: C78827 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: CL387748  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
123-I-MIP-1072
Iodine I 123 MIP-1072
Iofolastat I123

External Source Codes: 
PDQ Closed Trial Search ID 601822
PDQ Open Trial Search ID 601822 (check for NCI PDQ open clinical trial info)
NCI META CUI CL387748

Other Properties:
     Name Value (qualifiers indented underneath)
code C78827
Contributing_Source CTRP
Legacy_Concept_Name _123-I-MIP-1072
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C78827

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