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Version: 17.06d (Release date: 2017-06-26)
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Zirconium Zr 89 Cetuximab (Code C78473)

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Terms & Properties

Preferred Name: Zirconium Zr 89 Cetuximab

Definition: A radioimmunoconjugate comprised of the recombinant chimeric monoclonal antibody cetuximab labeled with the radioisotope zirconium Zr 89 (Zr 89) with radioisotopic activity and potential imaging use. The antibody moiety of zirconium Zr 89 cetuximab binds to the extracellular domain of the epidermal growth factor receptor (EGFR). Upon binding, the radioisotope moiety may be detected using positron emission tomography (PET), allowing the imaging and quantification of EGFR-expressing tumor cells. EGFR is a tyrosine kinase that may be overexpressed on the cell surfaces of various tumor cell types.

Label: Zirconium Zr 89 Cetuximab

NCI Thesaurus Code: C78473 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: CL387588  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Cetuximab-Zirconium-89
Cetuximab-Zr-89
Zirconium-89-Labeled Cetuximab
Zirconium Zr 89 Cetuximab

External Source Codes: 
PDQ Closed Trial Search ID 600183
PDQ Open Trial Search ID 600183 (check for NCI PDQ open clinical trial info)
NCI META CUI CL387588

Other Properties:
     Name Value (qualifiers indented underneath)
code C78473
Legacy_Concept_Name Zirconium-Zr_89_Cetuximab
Semantic_Type Amino Acid, Peptide, or Protein
Semantic_Type Indicator, Reagent, or Diagnostic Aid

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C78473

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