skip navigation links
National Cancer Institute
EVS Logo NCI Term Browser Enterprise Vocabulary Services
Terminologies Value Sets Mappings
Version: 16.11d (Release date: 2016-11-28)
SearchBox Top
SearchBox Bottom
HLA-A*2402-Restricted VEGFR1 Peptide Vaccine (Code C77869)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: HLA-A*2402-Restricted VEGFR1 Peptide Vaccine

Definition: A cancer vaccine containing the HLA-A*2402-restricted vascular endothelial growth factor receptor 1 (VEGFR1) peptide epitope with potential immunostimulatory and antitumor activities. Upon administration, HLA-A*2402-restricted VEGFR1 peptide vaccine may stimulate a cytotoxic T lymphocyte (CTL) response against tumor cells expressing VEGFR 1 peptide, resulting in tumor cell lysis and decreased tumor growth. HLA-A*2402 is an MHC class I molecule that presents antigenic peptides to CD8+ T cells; epitope design restricted to epitopes that bind most efficiently to HLA-A*2402 may improve antigenic peptide immunogenicity.

Label: HLA-A*2402-Restricted VEGFR1 Peptide Vaccine

NCI Thesaurus Code: C77869 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: CL387277  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
HLA-A*2402-Restricted VEGFR1 Peptide Vaccine

External Source Codes: 
PDQ Closed Trial Search ID 597662
PDQ Open Trial Search ID 597662 (check for NCI PDQ open clinical trial info)
NCI META CUI CL387277

Other Properties:
Name Value (qualifiers indented underneath)
code C77869
Legacy_Concept_Name HLA-A_2402-Restricted_VEGFR1_Peptide_Vaccine
Semantic_Type Amino Acid, Peptide, or Protein
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C77869

Mainbox Bottom