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Version: 16.11d (Release date: 2016-11-28)
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Gadobenate Dimeglumine (Code C77547)

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Terms & Properties

Preferred Name: Gadobenate Dimeglumine

Definition: A gadolinium-based paramagnetic contrast agent. When placed in a magnetic field, gadobenate dimeglumine produces a large magnetic moment and so a large local magnetic field, which can enhance the relaxation rate of nearby protons; as a result, the signal intensity of tissue images observed with magnetic resonance imaging (MRI) may be enhanced. Because this agent is preferentially taken up by normal functioning hepatocytes, normal hepatic tissue is enhanced with MRI while tumor tissue is unenhanced. In addition, because gadobenate dimeglumine is excreted in the bile, it may be used to visualize the biliary system using MRI.

NCI-GLOSS Definition: A drug used in MRI to help make clear pictures of blood vessels in the brain, spine, and nearby tissues. It is also being studied as a way to find abnormal areas in the liver and other organs and to help diagnose cancer. Gadobenate dimeglumine is a type of contrast agent.

Label: Gadobenate Dimeglumine

NCI Thesaurus Code: C77547 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0209453  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
(4RS)-[4-carboxy-5,8,11-tris(carboxymethyl)-1-phenyl-2-oxa-5,8,11-triazatridecan-13-oato(5-)] gadolinate(2-) dihydrogen compound with 1-deoxy-1-(methylamino)-D-glucitol (1:2)
GADOBENATE DIMEGLUMINE
Gadobenate Dimeglumine
gadobenate dimeglumine
Gd-BOPTA
MultiHance

External Source Codes: 
CAS Registry Number 127000-20-8 (see NLM ChemIDplus info)
FDA UNII Code 3Q6PPC19PO
PDQ Closed Trial Search ID 617168
PDQ Open Trial Search ID 617168 (check for NCI PDQ open clinical trial info)
UMLS CUI C0209453

Other Properties:
Name Value (qualifiers indented underneath)
Chemical_Formula C22H28N3O11.2C7H17NO5.Gd
code C77547
Contributing_Source FDA
Legacy_Concept_Name Gadobenate_Dimeglumine
Semantic_Type Indicator, Reagent, or Diagnostic Aid
Semantic_Type Organic Chemical

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C77547

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