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Version: 16.11d (Release date: 2016-11-28)
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Alogliptin (Code C76906)

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Terms & Properties

Preferred Name: Alogliptin

Definition: A selective, orally bioavailable, pyrimidinedione-based inhibitor of dipeptidyl peptidase 4 (DPP-4), with hypoglycemic activity. In addition to its effect on glucose levels, alogliptin may inhibit inflammatory responses by preventing the toll-like receptor 4 (TLR-4)-mediated formation of proinflammatory cytokines.

Label: Alogliptin

NCI Thesaurus Code: C76906 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C1958126  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
ALOGLIPTIN
Alogliptin
Benzonitrile, 2-[[6-[(3R)-3-amino-1-piperidinyl]-3,4-dihydro-3-methyl-2,4-dioxo-1(2H)- pyrimidinyl]methyl]-

External Source Codes: 
CAS Registry Number 850649-61-5 (see NLM ChemIDplus info)
FDA UNII Code JHC049LO86
UMLS CUI C1958126

Other Properties:
Name Value (qualifiers indented underneath)
Chemical_Formula C18H21N5O2
code C76906
Contributing_Source FDA
Legacy_Concept_Name Alogliptin
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C76906

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