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Version: 17.06d (Release date: 2017-06-26)
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Teloxantrone Hydrochloride (Code C74544)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: Teloxantrone Hydrochloride

Definition: The hydrochloride salt of an anthrapyrazole antineoplastic antibiotic. Teloxantrone intercalates into DNA and interacts with topoisomerase II, thereby inhibiting DNA replication and repair, as well as RNA and protein synthesis

Label: Teloxantrone Hydrochloride

NCI Thesaurus Code: C74544 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0970561  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Anthra(1,9-cd)pyrazol-6(2H)-one,7,10-dihydroxy-2-(2-((2-hydroxyethyl)amino)ethyl)-5-((2-(methylamino)ethyl)amino) Dihydrochloride
CI-937
DUP 937
Moxantrazole Hydrochloride
Teloxantrone Hydrochloride
TELOXANTRONE HYDROCHLORIDE

External Source Codes: 
CAS Registry Number 132937-88-3 (see NLM ChemIDplus info)
FDA UNII Code 7ZQK8VIO6V
NSC Code 355644 (see NCI DTP info)
PDQ Closed Trial Search ID 39411
PDQ Open Trial Search ID 39411 (check for NCI PDQ open clinical trial info)
UMLS CUI C0970561

Other Properties:
     Name Value (qualifiers indented underneath)
Chemical_Formula C21H25N5O4.2HCl.H2O
code C74544
Contributing_Source FDA
Legacy_Concept_Name Teloxantrone_Hydrochloride
Semantic_Type Organic Chemical
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C74544

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