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Version: 17.06d (Release date: 2017-06-26)
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Glycosylated Recombinant Human G-CSF AVI-014 (Code C74520)

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Terms & Properties

Preferred Name: Glycosylated Recombinant Human G-CSF AVI-014

Definition: A glycosylated form of a recombinant agent that is chemically identical to or similar to endogenous human granulocyte colony-stimulating factor (G-CSF) and is produced using transgenic biotechnology. Transgenic hens carrying recombinant human G-CSF cDNA express the naturally glycosylated recombinant human protein in egg albumen from which glycosylated recombinant human G-CSF AVI-014 is isolated. Produced endogenously by monocytes, fibroblasts, and endothelial cells, G-CSF binds to and activates specific cell surface receptors, stimulating neutrophil progenitor proliferation and differentiation and selected neutrophil functions.

Label: Glycosylated Recombinant Human G-CSF AVI-014

NCI Thesaurus Code: C74520 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: CL376144  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
AVI-014
Glycosylated Recombinant Human G-CSF AVI-014

External Source Codes: 
PDQ Closed Trial Search ID 560209
PDQ Open Trial Search ID 560209 (check for NCI PDQ open clinical trial info)
NCI META CUI CL376144

Other Properties:
     Name Value (qualifiers indented underneath)
code C74520
Legacy_Concept_Name Glycosylated_Recombinant_Human_G-CSF_AVI-014
Semantic_Type Amino Acid, Peptide, or Protein
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C74520

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