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Version: 16.11d (Release date: 2016-11-28)
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Picibanil (Code C745)

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Terms & Properties

Preferred Name: Picibanil

Definition: A lyophilized formulation containing cultures of a low-virulent strain of Streptococcus pyogenes, treated and killed with pencillin G, with potential sclerosing, immunostimulating and antineoplastic activity. Besides from picibanil's direct damaging effect as a sclerosing agent, it seems to have multiple effects on the immune system as a non-specific immunostimulant. Picibanil activates the host immune system by stimulating the activity of natural killer cells, macrophages and lymphocytes, and by enhancing the production of several key immune mediators, including interleukins and tumor necrosis factor.

Label: Picibanil

NCI Thesaurus Code: C745 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0031875  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
OK-432
Picibanil

External Source Codes: 
CAS Registry Number 39325-01-4 (see NLM ChemIDplus info)
FDA UNII Code 2F42BH7X2L
PDQ Closed Trial Search ID 489137
PDQ Open Trial Search ID 489137 (check for NCI PDQ open clinical trial info)
UMLS CUI C0031875

Other Properties:
Name Value (qualifiers indented underneath)
code C745
Contributing_Source FDA
Legacy_Concept_Name OK-432
Semantic_Type Organic Chemical
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C745

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