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Version: 17.12d (Release date: 2017-12-26)
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Regadenoson (Code C74420)

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Terms & Properties

Preferred Name: Regadenoson

Definition: An adenosine derivative and selective A2A adenosine receptor agonist with coronary vasodilating activity. Upon administration, regadenoson selectively binds to and activates the A2A adenosine receptor, which induces coronary vasodilation. This leads to an increase in coronary blood flow and enhances myocardial perfusion. Compared to adenosine, regadenoson has a longer half-life and shows higher selectivity towards the A2A adenosine receptor. This agent is a very weak agonist for the A1 adenosine receptor and has negligible affinity for the A2B and A3 adenosine receptors.

Label: Regadenoson

NCI Thesaurus Code: C74420 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C1698215  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Adenosine, 2-(4-((methylamino)carbonyl)-1H-pyrazol-1-yl)-

External Source Codes: 
CAS Registry Number 313348-27-5 (see NLM ChemIDplus info)
PDQ Closed Trial Search ID 761605
PDQ Open Trial Search ID 761605 (check for NCI PDQ open clinical trial info)
UMLS CUI C1698215

Other Properties:
     Name Value (qualifiers indented underneath)
Chemical_Formula C15H18N8O5.H2O
code C74420
Contributing_Source FDA
Legacy_Concept_Name Regadenoson
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  


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