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Version: 16.11d (Release date: 2016-11-28)
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Yttrium Y 90 Anti-CD66 Monoclonal Antibody BW 250/183 (Code C74094)

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Terms & Properties

Preferred Name: Yttrium Y 90 Anti-CD66 Monoclonal Antibody BW 250/183

Definition: A radioimmunoconjugate consisting of the murine IgG1 monoclonal antibody BW250/183 labeled with yttrium Y 90 with potential radioimmunotherapeutic activity. Yttrium Y 90 anti-CD66 monoclonal antibody BW 250/183 binds to a 95 kD nonspecific cross-reacting antigen (CD66b or NCA-95) on granulocytes, selectively delivering a cytotoxic dose of Y 90 beta radiation to CD66b-expressing cells. CD66b, a member of the carcinoembryonic antigen (CEA) family with an unknown function, appears early in the differentiation of granulopoietic cells and is expressed on the cell surface of almost all human granulocytes and their more mature precursors.

Label: Yttrium Y 90 Anti-CD66 Monoclonal Antibody BW 250/183

NCI Thesaurus Code: C74094 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: CL388336  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
BW 250/183
Yttrium Y 90 Anti-CD66 Monoclonal Antibody BW 250/183

External Source Codes: 
PDQ Closed Trial Search ID 589964
PDQ Open Trial Search ID 589964 (check for NCI PDQ open clinical trial info)
NCI META CUI CL388336

Other Properties:
Name Value (qualifiers indented underneath)
code C74094
Legacy_Concept_Name Yttrium_Y_90_Anti-CD66_Monoclonal_Antibody_BW250_183
Semantic_Type Amino Acid, Peptide, or Protein
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C74094

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