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Version: 16.11d (Release date: 2016-11-28)
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Yttrium Y 90 Anti-CD19 Monoclonal Antibody BU12 (Code C74092)

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Terms & Properties

Preferred Name: Yttrium Y 90 Anti-CD19 Monoclonal Antibody BU12

Definition: A radioimmunoconjugate consisting of the murine IgG1 anti-CD19 monoclonal antibody (MoAb) BU12 labeled with the beta-emitting radioisotope yttrium Y 90 with radioisotopic and antibody activities. Yttrium Y 90 anti-CD19 monoclonal antibody BU12 binds to the CD19 molecule, specifically delivering cytotoxic beta radiation to CD19-expressing B cells. CD19 is a membrane antigen that is widely expressed during B-cell development, from pro-B-cell to early plasma cell stages.

Display Name: Yttrium Y 90 Anti-CD19 Monoclonal Antibody BU12

Label: Yttrium Y 90 Anti-CD19 Monoclonal Antibody BU12

NCI Thesaurus Code: C74092 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: CL383553  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Yttrium Y 90 Anti-CD19 Monoclonal Antibody BU12

External Source Codes: 
PDQ Closed Trial Search ID 592567
PDQ Open Trial Search ID 592567 (check for NCI PDQ open clinical trial info)
NCI META CUI CL383553

Other Properties:
Name Value (qualifiers indented underneath)
code C74092
Contributing_Source CTRP
Legacy_Concept_Name Yttrium_Y_90_Anti-CD19_Monoclonal_Antibody_BU12
Semantic_Type Amino Acid, Peptide, or Protein
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C74092

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