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Version: 17.06d (Release date: 2017-06-26)
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WT1-Sensitized Allogeneic T-Lymphocytes (Code C74091)

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Terms & Properties

Preferred Name: WT1-Sensitized Allogeneic T-Lymphocytes

Definition: A population of allogeneic T-cells sensitized with Wilms tumor 1 (WT1) antigen with potential immunostimulatory and antineoplastic activities. Upon administration, WT1-sensitized T cells may bind to and lyse WT1-expressing tumor cells. WT1 antigen, a zinc finger DNA-binding protein acting as a transcriptional activator or repressor depending on the cellular or chromosomal context, is overexpressed in leukemic cells and in a vast number of nonhematological solid tumors.

Display Name: WT1-Sensitized Allogeneic T-Lymphocytes

Label: WT1-Sensitized Allogeneic T-Lymphocytes

NCI Thesaurus Code: C74091 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C2349140  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
WT1-Sensitized Allogeneic T-Lymphocytes

External Source Codes: 
PDQ Closed Trial Search ID 589317
PDQ Open Trial Search ID 589317 (check for NCI PDQ open clinical trial info)
UMLS CUI C2349140

Other Properties:
     Name Value (qualifiers indented underneath)
code C74091
Contributing_Source CTRP
Legacy_Concept_Name WT1-Sensitized_Allogeneic_T-Lymphocytes
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C74091

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