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Version: 17.02d (Release date: 2016-02-27)
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URLC10-TTK-KOC1-VEGFR1-VEGFR2 Multipeptide Vaccine (Code C74088)

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Terms & Properties

Preferred Name: URLC10-TTK-KOC1-VEGFR1-VEGFR2 Multipeptide Vaccine

Definition: A cancer vaccine containing five peptide epitopes with potential immunostimulatory and antitumor activity. Peptide epitopes in this vaccine are derived from: URLC10 (up-regulated lung cancer 10), TTK (TTK protein kinase), KOC1 (IGF II mRNA Binding Protein 3) and VEGFRs (vascular endothelial growth factor receptors) 1 and 2. Upon administration, URLC10-TTK-KOC1-VEGFR1-VEGFR2 multipeptide vaccine may stimulate a cytotoxic T lymphocyte (CTL) response against tumor cells expressing URLC10, TTK, KCO1, VEGFR 1 and 2 peptides, resulting in cell lysis and decreased tumor growth.

Label: URLC10-TTK-KOC1-VEGFR1-VEGFR2 Multipeptide Vaccine

NCI Thesaurus Code: C74088 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: CL383869  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
URLC10-TTK-KOC1-VEGFR1-VEGFR2 Multipeptide Vaccine

External Source Codes: 
PDQ Closed Trial Search ID 590716
PDQ Open Trial Search ID 590716 (check for NCI PDQ open clinical trial info)
NCI META CUI CL383869

Other Properties:
Name Value (qualifiers indented underneath)
code C74088
Legacy_Concept_Name URLC10-TTK-KOC1-VEGFR1-VEGFR2_Multipeptide_Vaccine
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C74088

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