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Version: 17.06d (Release date: 2017-06-26)
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Tasquinimod (Code C74080)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: Tasquinimod

Definition: A quinoline-3-carboxamide linomide analogue with antiangiogenic and potential antineoplastic activities. Tasquinimod has been shown to decrease blood vessel density but the exact mechanism of action is not known. This agent has also been shown to augment the antineoplastic effects of docetaxel and androgen ablation in a murine model of prostate cancer involving human prostate cancer xenografts.

Display Name: Tasquinimod

Label: Tasquinimod

NCI Thesaurus Code: C74080 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C1956491  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
ABR-215050
TASQ
Tasquinimod
TASQUINIMOD

External Source Codes: 
CAS Registry Number 254964-60-8 (see NLM ChemIDplus info)
FDA UNII Code 756U07KN1R
PDQ Closed Trial Search ID 581229
PDQ Open Trial Search ID 581229 (check for NCI PDQ open clinical trial info)
UMLS CUI C1956491

Other Properties:
     Name Value (qualifiers indented underneath)
Chemical_Formula C20H17F3N2O4
code C74080
Contributing_Source CTRP
Contributing_Source FDA
Legacy_Concept_Name Tasquinimod
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C74080

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