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National Cancer Institute
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Version: 17.06d (Release date: 2017-06-26)
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Liposomal MnSOD Plasmid (Code C74054)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: Liposomal MnSOD Plasmid

Definition: A plasmid DNA encoding human manganese superoxide dismutase (MnSOD) and liposomally encapsulated with potential chemoprotective activity. When administered orally and localizing in the esophagus, MnSOD-plasmid liposomes express MnSOD, which scavenges reactive oxygen species (ROS); MnSOD scavenging of ROS may result in a reduction in ROS-mediated lipid peroxidation, apoptosis, and micro-ulceration in the epithelial lining of the esophagus.

Display Name: Liposomal MnSOD Plasmid

Label: Liposomal MnSOD Plasmid

NCI Thesaurus Code: C74054 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: CL383936  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Liposomal MnSOD Plasmid
MnSOD-PL
MnSOD Plasmid Liposomes

External Source Codes: 
PDQ Closed Trial Search ID 589811
PDQ Open Trial Search ID 589811 (check for NCI PDQ open clinical trial info)
NCI META CUI CL383936

Other Properties:
     Name Value (qualifiers indented underneath)
code C74054
Contributing_Source CTRP
Legacy_Concept_Name Liposomal_MnSOD_Plasmid
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C74054

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