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Version: 16.11d (Release date: 2016-11-28)
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Iodine I 131-6-Beta-Iodomethyl-19-Norcholesterol (Code C74052)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: Iodine I 131-6-Beta-Iodomethyl-19-Norcholesterol

Definition: A radioiodine-labeled cholesterol analogue with radioisotopic activity. Iodine 131-I-6-beta-iodomethyl-19-norcholesterol accumulates in tissues where steroid hormones are produced, including the adrenal cortex and, to a lesser extent, the ovaries and the testes. After binding to low-density lipoprotein (LDL) receptors in the adrenal cortex, this agent is internalized, permitting scintigraphic localization of areas of adrenocortical glucocorticoid, mineralocorticoid and androgen secretion, and the scintigraphic assessment of adrenocortical function.

Label: Iodine I 131-6-Beta-Iodomethyl-19-Norcholesterol

NCI Thesaurus Code: C74052 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C2346585  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
I-131 NP-59
Iodine I 131-6-Beta-Iodomethyl-19-Norcholesterol
Radioiodine-Labeled Norcholesterol

External Source Codes: 
PDQ Closed Trial Search ID 586372
PDQ Open Trial Search ID 586372 (check for NCI PDQ open clinical trial info)
UMLS CUI C2346585

Other Properties:
Name Value (qualifiers indented underneath)
code C74052
Legacy_Concept_Name Iodine_I_131-6-Beta-Iodomethyl-19-Norcholesterol
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C74052

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