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Version: 17.06d (Release date: 2017-06-26)
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Iodine I 124-Iodo-Azomycin Galactopyranoside (Code C74050)

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Terms & Properties

Preferred Name: Iodine I 124-Iodo-Azomycin Galactopyranoside

Definition: A diagnostic radiopharmaceutical comprised of iodo-azomycin galactopyranoside (IAZGP) labeled with the positron-emitting radioisotope iodine I 124 and used as an imaging agent. Iodine I 124 iodo-azomycin galactopyranoside (I-124 IAZGP) is reduced under hypoxic conditions, covalently binding to macromolecules in hypoxic cells. After incorporation into hypoxic tumor cell DNA, I-124 IAZGP can be localized and quantified using positron emission tomography (PET), allowing a quantitative assessment of hypoxic tumor burden. IAZGP appears to have a higher water solubility and faster clearance from normal tissue than traditional imidazole tracers.

Label: Iodine I 124-Iodo-Azomycin Galactopyranoside

NCI Thesaurus Code: C74050 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: CL383497  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
I-124 IAZGP
Iodine I 124-Iodo-Azomycin Galactopyranoside

External Source Codes: 
PDQ Closed Trial Search ID 587196
PDQ Open Trial Search ID 587196 (check for NCI PDQ open clinical trial info)
NCI META CUI CL383497

Other Properties:
     Name Value (qualifiers indented underneath)
code C74050
Legacy_Concept_Name Iodine_I_124-Iodo-Azomycin_Galactopyranoside
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C74050

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