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Version: 17.06d (Release date: 2017-06-26)
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Iobenguane Sulfate I-123 (Code C74049)

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Terms & Properties

Preferred Name: Iobenguane Sulfate I-123

Definition: The neurotransmitter analogue 3-nitrobenzylguanidine conjugated to iodine I 123 and used as a gamma-emitting imaging agent. The adrenergic tissue uptake and storage of I-123 metaiodobenzylguanidine (I-123 MIBG) mimics that of norepinephrine (NE). The distribution of this agent enables the scintigraphic imaging of neural crest tumors, such as neuroblastoma and pheochromocytoma.

Label: Iobenguane Sulfate I-123

NCI Thesaurus Code: C74049 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C2346581  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Iobenguane Sulfate I-123
Iodine I 123-Metaiodobenzylguanidine

External Source Codes: 
CAS Registry Number 139755-80-9 (see NLM ChemIDplus info)
FDA UNII Code 23X1185WBO
PDQ Closed Trial Search ID 586662
PDQ Open Trial Search ID 586662 (check for NCI PDQ open clinical trial info)
UMLS CUI C2346581

Other Properties:
     Name Value (qualifiers indented underneath)
Chemical_Formula 2C8H10IN3.H2SO4
code C74049
Contributing_Source FDA
Legacy_Concept_Name Iodine_I_123-Metaiodobenzylguanidine
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  


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