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Version: 17.06d (Release date: 2017-06-26)
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Indium In 111 Monoclonal Antibody HuPAM4 (Code C74048)

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Terms & Properties

Preferred Name: Indium In 111 Monoclonal Antibody HuPAM4

Definition: The humanized monoclonal antibody huPAM4, directed against the pancreatic cancer antigen MUC-1 and labeled with the gamma-emitting radioisotope indium In 111, with radioisotopic and antibody activities. Upon administration, indium In 111 monoclonal antibody huPAM4 may bind to MUC-1-positive tumor cells, allowing radioimmunolocalization with gamma scintigraphy. Overexpressed by many tumor cell types, MUC-1 antigen, a mammary-type apomucin, is a high-molecular-weight transmembrane glycoprotein.

Label: Indium In 111 Monoclonal Antibody HuPAM4

NCI Thesaurus Code: C74048 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: CL383546  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
111 In- Labeled Humanized PAM4 IgG
In-111-HuPAM4
Indium In 111 Monoclonal Antibody HuPAM4

External Source Codes: 
PDQ Closed Trial Search ID 590705
PDQ Open Trial Search ID 590705 (check for NCI PDQ open clinical trial info)
NCI META CUI CL383546

Other Properties:
     Name Value (qualifiers indented underneath)
code C74048
Legacy_Concept_Name Indium_In_111_Monoclonal_Antibody_HuPAM4
Semantic_Type Amino Acid, Peptide, or Protein
Semantic_Type Indicator, Reagent, or Diagnostic Aid

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C74048

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