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Version: 16.11d (Release date: 2016-11-28)
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Indium In 111 Girentuximab (Code C74047)

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Terms & Properties

Preferred Name: Indium In 111 Girentuximab

Definition: A radioimmunoconjugate comprised of the chimeric monoclonal antibody girentuximab conjugated with the gamma-emitting radioisotope indium In 111. Indium In 111 girentuximab binds to G250, allowing the localization of G250-expressing tumor cells using gamma scintigraphy. Found in the majority of renal cell carcinomas (RCCs), G250 or carbonic anhydrase isozyme IX (CA IX) is a cell surface tumor-associated antigen (TAA).

Label: Indium In 111 Girentuximab

NCI Thesaurus Code: C74047 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: CL383509  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
In-111 MoAbG250
Indium In 111 Girentuximab

External Source Codes: 
PDQ Closed Trial Search ID 588355
PDQ Open Trial Search ID 588355 (check for NCI PDQ open clinical trial info)
NCI META CUI CL383509

Other Properties:
Name Value (qualifiers indented underneath)
code C74047
Legacy_Concept_Name Indium_I_111_Chimeric_Monoclonal_Antibody_G250
Semantic_Type Amino Acid, Peptide, or Protein
Semantic_Type Indicator, Reagent, or Diagnostic Aid

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C74047

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