skip navigation links
National Cancer Institute
EVS Logo NCI Term Browser Enterprise Vocabulary Services
Terminologies Value Sets Mappings
Version: 16.10e (Release date: 2016-10-31)
SearchBox Top
SearchBox Bottom
Idiotype-Pulsed Autologous Dendritic Cell Vaccine APC8020 (Code C74042)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: Idiotype-Pulsed Autologous Dendritic Cell Vaccine APC8020

Definition: A cell-based cancer vaccine composed of autologous dendritic cells (DCs) pulsed with tumor-derived clonal immunoglobulin (Ig) with potential immunostimulatory and antineoplastic activities. Upon administration, idiotype-pulsed autologous dendritic cell vaccine APC8020, containing idiotype (Id) protein structures that can be recognized by antibodies and by CD41 T lymphocytes and CD81 T lymphocytes, may stimulate antitumoral cytotoxic T lymphocyte (CTL) and antibody responses against Id-expressing tumor cells. The Id represents the unique antigenic determinants in the variable regions of the clonal Ig.

Label: Idiotype-Pulsed Autologous Dendritic Cell Vaccine APC8020

NCI Thesaurus Code: C74042 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: CL383479  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
APC8020
Idiotype-Pulsed Autologous Dendritic Cell Vaccine APC8020
Mylovenge

External Source Codes: 
PDQ Closed Trial Search ID 584999
PDQ Open Trial Search ID 584999 (check for NCI PDQ open clinical trial info)
NCI META CUI CL383479

Other Properties:
Name Value (qualifiers indented underneath)
code C74042
Legacy_Concept_Name Idiotype-Pulsed_Autologous_Dendritic_Cell_Vaccine_APC8020
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C74042

Mainbox Bottom