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Version: 17.12d (Release date: 2017-12-26)
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Idiotype-Pulsed Autologous Dendritic Cell Vaccine APC8020 (Code C74042)

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Terms & Properties

Preferred Name: Idiotype-Pulsed Autologous Dendritic Cell Vaccine APC8020

Definition: A cell-based cancer vaccine composed of autologous dendritic cells (DCs) pulsed with tumor-derived clonal immunoglobulin (Ig) with potential immunostimulatory and antineoplastic activities. Upon administration, idiotype-pulsed autologous dendritic cell vaccine APC8020, containing idiotype (Id) protein structures that can be recognized by antibodies and by CD41 T lymphocytes and CD81 T lymphocytes, may stimulate antitumoral cytotoxic T lymphocyte (CTL) and antibody responses against Id-expressing tumor cells. The Id represents the unique antigenic determinants in the variable regions of the clonal Ig.

Label: Idiotype-Pulsed Autologous Dendritic Cell Vaccine APC8020

NCI Thesaurus Code: C74042 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: CL383479  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Idiotype-Pulsed Autologous Dendritic Cell Vaccine APC8020

External Source Codes: 
PDQ Closed Trial Search ID 584999
PDQ Open Trial Search ID 584999 (check for NCI PDQ open clinical trial info)

Other Properties:
     Name Value (qualifiers indented underneath)
code C74042
Legacy_Concept_Name Idiotype-Pulsed_Autologous_Dendritic_Cell_Vaccine_APC8020
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  


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