skip navigation links
National Cancer Institute
EVS Logo NCI Term Browser Enterprise Vocabulary Services
Terminologies Value Sets Mappings
Version: 17.06d (Release date: 2017-06-26)
SearchBox Top
SearchBox Bottom
GD2 Lactone/GD3 Lactone-KLH Conjugate Bivalent Vaccine (Code C74035)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: GD2 Lactone/GD3 Lactone-KLH Conjugate Bivalent Vaccine

Definition: A cancer vaccine, containing epitopes of the gangliosides GD2 and GD3 conjugated with the immunostimulant keyhole limpet hemocyanin (KLH), with potential antineoplastic activity. Vaccination with GD2 lactone/GD3 lactone-KLH conjugate bivalent vaccine may elicit antibodies against tumor cells expressing either epitope, resulting in complement-mediated cytotoxicity (CMC) and antibody-dependent cell-mediated cytotoxicity (ADCC). Located primarily in the nervous system, gangliosides, such as GD2 and GD3, are cell membrane components involved in cellular recognition and cell-cell communication.

Display Name: GD2 Lactone/GD3 Lactone-KLH Conjugate Bivalent Vaccine

Label: GD2 Lactone/GD3 Lactone-KLH Conjugate Bivalent Vaccine

NCI Thesaurus Code: C74035 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: CL383507  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
GD2 Lactone/GD3 Lactone-KLH Conjugate Bivalent Vaccine

External Source Codes: 
PDQ Closed Trial Search ID 588002
PDQ Open Trial Search ID 588002 (check for NCI PDQ open clinical trial info)
NCI META CUI CL383507

Other Properties:
     Name Value (qualifiers indented underneath)
code C74035
Contributing_Source CTRP
Legacy_Concept_Name GD2_Lactone_GD3_Lactone-KLH_Conjugate_Bivalent_Vaccine
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C74035

Mainbox Bottom