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Version: 17.04d (Release date: 2017-04-24)
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Gallium Ga 68 F(ab')2-Trastuzumab (Code C74033)

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Terms & Properties

Preferred Name: Gallium Ga 68 F(ab')2-Trastuzumab

Definition: A radioimmunoconjugate consisting of a trastuzumab fragment labeled with the positron-emitting radioisotope gallium Ga 68 with radioisotopic and antibody activities. Upon administration, Ga-68-labeled F(ab')2-trastuzumab may bind to HER2-positive tumor cells, allowing radioimmunolocalization with positron emission tomography (PET). Trastuzumab is a recombinant humanized monoclonal antibody that selectively binds to the extracellular domain of human epidermal growth factor receptor 2 (HER2), overexpressed by many adenocarcinomas, particularly breast adenocarcinomas.

Label: Gallium Ga 68 F(ab')2-Trastuzumab

NCI Thesaurus Code: C74033 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C2348728  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Gallium Ga 68 F(ab')2-Trastuzumab
HERScan

External Source Codes: 
PDQ Closed Trial Search ID 590631
PDQ Open Trial Search ID 590631 (check for NCI PDQ open clinical trial info)
UMLS CUI C2348728

Other Properties:
     Name Value (qualifiers indented underneath)
code C74033
Legacy_Concept_Name Gallium_Ga_68_F_ab_2-Trastuzumab
Semantic_Type Amino Acid, Peptide, or Protein
Semantic_Type Indicator, Reagent, or Diagnostic Aid

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C74033

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