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National Cancer Institute
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Version: 17.08d (Release date: 2017-08-28)
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DC-OVA Vaccine (Code C73986)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: DC-OVA Vaccine

Definition: An autologous, multivalent dendritic cell vaccine targeting ovarian cancer with potential immunostimulating and antineoplastic activities. DC-OVA vaccine is produced in vitro by pulsing autologous dendritic cells with killed autologous primary ovarian tumors as a source of tumor-associated antigens (TAAs); the pulsed DCs are then matured using various cytokines. Upon administration, DC-OVA vaccine may stimulate a cytotoxic T lymphocyte (CTL) response against ovarian cancer TAA-expressing ovarian cancer cells.

Label: DC-OVA Vaccine

NCI Thesaurus Code: C73986 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: CL376121  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
DC-OVA Vaccine

External Source Codes: 
PDQ Closed Trial Search ID 557721
PDQ Open Trial Search ID 557721 (check for NCI PDQ open clinical trial info)

Other Properties:
     Name Value (qualifiers indented underneath)
code C73986
Legacy_Concept_Name DC-OVA_Vaccine
Semantic_Type Cell
Semantic_Type Immunologic Factor

Additional Concept Data: 
Defined Fully by Roles: No  


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