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Version: 17.06d (Release date: 2017-06-26)
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Raltegravir Potassium (Code C73823)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: Raltegravir Potassium

Definition: The orally bioavailable potassium salt of a human immunodeficiency virus (HIV) integrase strand transfer inhibitor (HIV-1 INSTI) with HIV-1 antiviral activity. Raltegravir binds to and inhibits integrase, an HIV enzyme that inserts viral genetic material into the genetic material of the infected human cell. Inhibition of integrase prevents insertion of HIV DNA into the human DNA genome, thus blocking HIV replication.

Display Name: Raltegravir Potassium

Label: Raltegravir Potassium

NCI Thesaurus Code: C73823 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C1966407  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Isentress
N-[(4-Fluorophenyl)methyl]-1,6-dihydro-5-hydroxy-1-methyl-2-[1-methyl-1-[[ (5-methyl-1,3,4-oxadiazol-2-yl)carbonyl]amino]ethyl]-6-oxo-4-pyrimidinecarboxamide Monopotassium Salt
Raltegravir Potassium
RALTEGRAVIR POTASSIUM

External Source Codes: 
CAS Registry Number 871038-72-1 (see NLM ChemIDplus info)
FDA UNII Code 43Y000U234
PDQ Closed Trial Search ID 658548
PDQ Open Trial Search ID 658548 (check for NCI PDQ open clinical trial info)
UMLS CUI C1966407

Other Properties:
     Name Value (qualifiers indented underneath)
Chemical_Formula C20H20FN6O5.K
code C73823
Contributing_Source CTRP
Contributing_Source FDA
Legacy_Concept_Name Raltegravir_Potassium
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C73823

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