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Version: 17.06d (Release date: 2017-06-26)
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Penicillin V Potassium (Code C730)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: Penicillin V Potassium

Definition: The potassium salt of penicillin V, a member of the penicillin antibiotic family with broad-spectrum bactericidal activity. Penicillin V binds to and inactivates penicillin-binding proteins (PBPs), enzymes located on the inner membrane of the bacterial cell wall, resulting in the weakening of the bacterial cell wall and cell lysis. PBPs participate in the terminal stages of assembling the bacterial cell wall, and in reshaping the cell wall during cell division. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity.

Label: Penicillin V Potassium

NCI Thesaurus Code: C730 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0700553  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Pen-Vee
Penicillin V Potassium
PENICILLIN V POTASSIUM

External Source Codes: 
CAS Registry Number 132-98-9 (see NLM ChemIDplus info)
FDA UNII Code 146T0TU1JB
ChEBI ID CHEBI:7967 (see ChEBI info)
PDQ Closed Trial Search ID 40795
PDQ Open Trial Search ID 40795 (check for NCI PDQ open clinical trial info)
UMLS CUI C0700553

Other Properties:
     Name Value (qualifiers indented underneath)
Chemical_Formula C16H17N2O5S.K
code C730
Contributing_Source FDA
Legacy_Concept_Name Penicillin_V
Semantic_Type Antibiotic
Semantic_Type Organic Chemical

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C730

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