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Version: 17.06d (Release date: 2017-06-26)
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Papaverine (Code C726)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: Papaverine

Definition: An opiate alkaloid isolated from the plant Papaver somniferum and produced synthetically. As a direct-acting smooth muscle relaxant, papaverine is not closely related to the other opium alkaloids in structure or pharmacological actions; its mechanism of action may involve the non-selective inhibition of phosphodiesterases and direct inhibition of calcium channels. This agent also exhibits antiviral activity against respiratory syncytial virus, cytomegalovirus, and HIV. (NCI04)

Display Name: Papaverine

Label: Papaverine

NCI Thesaurus Code: C726 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0030350  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Cerebid
Cerespan
Papaverine
PAPAVERINE
Pavabid
Pavacap
Pavatym
Robaxapap

External Source Codes: 
CAS Registry Number 58-74-2 (see NLM ChemIDplus info)
FDA UNII Code DAA13NKG2Q
ChEBI ID CHEBI:28241 (see ChEBI info)
NSC Code 136630 (see NCI DTP info)
PDQ Closed Trial Search ID 39545
PDQ Open Trial Search ID 39545 (check for NCI PDQ open clinical trial info)
UMLS CUI C0030350

Other Properties:
     Name Value (qualifiers indented underneath)
Accepted_Therapeutic_Use_For Ischemia, cerebral and peripheral
Chemical_Formula C20H21NO4
code C726
Contributing_Source CTRP
Contributing_Source FDA
Legacy_Concept_Name Papaverine
Semantic_Type Organic Chemical
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C726

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