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Version: 16.11d (Release date: 2016-11-28)
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Modified Vaccinia Ankara (Bavarian Nordic)-HER2 Vaccine (Code C71758)

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Terms & Properties

Preferred Name: Modified Vaccinia Ankara (Bavarian Nordic)-HER2 Vaccine

Definition: A cancer vaccine consisting of a proprietary, recombinant modified vaccinia Ankara (MVA) viral vector encoding an epitope of human epidermal growth factor receptor 2 (HER2) with potential antineoplastic activity. Upon administration, modified vaccinia Ankara (Bavarian Nordic)-HER2 vaccine may stimulate the host immune system to mount humoral and cytotoxic T lymphocyte responses against HER2-expressing tumor cells, resulting in tumor cell lysis. HER2, also known as ErbB-2, is a tyrosine kinase growth factor receptor and a member of the epidermal growth factor receptor family; it plays a significant role in the pathogenesis of some breast cancers.

Display Name: Modified Vaccinia Ankara (Bavarian Nordic)-HER2 Vaccine

Label: Modified Vaccinia Ankara (Bavarian Nordic)-HER2 Vaccine

NCI Thesaurus Code: C71758 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: CL376123  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Modified Vaccinia Ankara (Bavarian Nordic)-HER2 Vaccine
MVA-BN-HER2

External Source Codes: 
PDQ Closed Trial Search ID 558806
PDQ Open Trial Search ID 558806 (check for NCI PDQ open clinical trial info)
NCI META CUI CL376123

Other Properties:
Name Value (qualifiers indented underneath)
code C71758
Contributing_Source CTRP
Legacy_Concept_Name MVA-BN-HER2
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C71758

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