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Version: 17.06d (Release date: 2017-06-26)
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Intranasal Ketamine (Code C71709)

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Terms & Properties

Preferred Name: Intranasal Ketamine

Definition: An intranasal formulation of the synthetic cyclohexanone ketamine with analgesic and anesthetic activities. Although its mechanism of action is not well understood, ketamine appears to non-competitively block N-methyl-D-aspartate (NMDA) receptors and agonistically bind to and activate opioid mu and sigma receptors, thereby reducing pain perception, inducing sedation, and producing dissociative anesthesia.

Label: Intranasal Ketamine

NCI Thesaurus Code: C71709 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: CL376135  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Intranasal Ketamine

External Source Codes: 
PDQ Closed Trial Search ID 560167
PDQ Open Trial Search ID 560167 (check for NCI PDQ open clinical trial info)
NCI META CUI CL376135

Other Properties:
     Name Value (qualifiers indented underneath)
code C71709
Legacy_Concept_Name Intranasal_Ketamine
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C71709

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